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"Trend reversals triggered price declines in global equity markets, energy and precious metals which caught many CTAs on their back foot," said Sol Waksman, president of BarclayHedge. "However, managers properly positioned in agricultural markets, currencies and interest rates were able to profit."

While most sectors in the Barclay CTA Indices lost ground in September, three were in the black for the month. The Agricultural Traders Index gained 0.63% in September, the Currency Traders Index added 0.55%, the and the Financial & Metal Traders Index was up 0.16%.

Sectors in the red for the month included the Cryptocurrency Traders Index, down 10.88%, the MPI Barclay Elite Systematic Traders Index, off 1.47%, the Diversified Traders Index, losing 1.41%, the Systematic Traders Index, falling 0.92%, and the Discretionary Traders Index, shedding 0.75%.

Despite September's loss, the Cryptocurrency Traders Index set the pace for year-to-date gainers through September, up 61.54%. Other leading gainers included the Agricultural Traders Index, up 10.04%, the Currency Traders Index, returning 5.37%, the Discretionary Traders Index, gaining 4.35%, and the Systematic Traders Index, up 2.20%.

Again in September, the MPI Barclay Elite Systematic Traders Index was the lone sector in negative territory for the year-to-date, down 5.02%.

The Barclay BTOP50 Index, which tracks the performance of the largest CTAs that are still open for new investment, was down 1.41% in September. Year-to-date, the BTOP 50 has dropped 0.65%.